A review on role of Candida albicans in causing complications of Vulvovaginal candidiasis

Bhavya Arora, Prachi Tayal, Himanshu Raghav, Rashmi Mittal


Vulvo vaginal candidasis is vigrously spreading in 80% of VVC cases. Other species of Candida albicians like Candida glabrata, Candida tropicalis, and Candida krusei also causes VVC especially in HIV infected person. Various anti- fungal agents like miconzole and clotrimazole are studied regarding the treatment of the VVC. More than 250 strains are examined by using an in vitro studies in 1993 and no resistance was found on ketoconazole, itraconazole and clotrimazole. VVC also commonly occur due to genitor urinary candidiasis balanitis, candiduria in both sexes and balanoposthitis in men. Immunocompetent as well as immune comprised patients were also prone to this disease. Candida albicians also causes the inflammation of the glans penis. Various projects based upon the animal models were performed for the treatment of vaginial candidiais. 20 – 55 % of womens are asyptomatic vaginal colonization with candida species. It is strongly believed that fungal infection is not sexual transmitting disease. But the rout of transmission is oral and estrogen dependent.

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