Role of adhesion molecules in enhancing complexity of Candidiasis

Preeti Raperia , Narender Chaudhry, Rashmi Mittal

Abstract


Microbial adhesion plays an extensive role in enhancing complexity of any disease. Micro-organisms interacts with host organisms via adhesion molecules which further facilitates the activation of signaling pathways ultimately enhancing complications of diseases. Integrin, fibronectin and E-cadherin are the major adhesion molecules. Glycosylphosphatidylinositol (GPI) linked cell surface glycoproteins and agglutinin like sequences genes (ALSs) played an extensive role in adhesion of Candida albicans to the host which further leads to onset of several diseases like vulvovaginal candidiasis. Adhesion molecules have always remained a major target in order to combat the candidiasis. The present review article is an attempt to briefly explain the role of adhesion molecules which are involved in enhancing complexity of candidiasis.

Full Text:

PDF

Refbacks

  • There are currently no refbacks.




Copyright (c) 2018 Preeti Raperia1 , Narender Chaudhry, Rashmi Mittal

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.